For over a decade, we have been helping scientists make groundbreaking discoveries that transform the scientific community and lead to innovative therapeutic breakthroughs.
See more about what they are doing with our CRISPR solutions to uncover how we can be your Guide towards gene editing success.
Synthego is one of the most promising and necessary companies to emerge in the field of genome engineering. By increasing access to this scientific advancement, Synthego will have an immediate impact on life sciences researchers and is poised to transform the industry by making the application of CRISPR simpler, faster, and more valuable to innovators previously unable to realize its full potential.
We are so happy with the Synthego guides that we are starting to order from Synthego for all of my other projects. For my muscular dystrophy samples as well, we ordered guides from Synthego.
Synthego encourages beginners, like us, to use CRISPR-Cas9 as our knockout method by providing fast and low-cost services. Synthego sgRNA gave us a chance to move forward to CRISPR gene editing and determine the critical role of our molecule of interest!
What I really favour about Synthego's product is their ready-to-go format, which only requires resuspension of the sgRNA prior to RNP formation. I also got the chance to interact with both ordering and technical support and found both of them very helpful and immediate.
Synthego's synthetic sgRNAs, in addition to their standard benefits (speed of preparation, consistency, stability) are the simplest way to go from a sequence to a hands-on experiment, and are an extraordinary pedagogical tool for teaching the basics of genome editing.
We were very pleased with Synthego's customer service and quality of the reagents. We observed impressive mutation rates in primary cells, including at difficult target loci where we had previously struggled to achieve genome editing.
Using the RNP format is the only way [to achieve high editing efficiencies]. I've tried doing it with plasmids or DNA in general, and the B cells just rejected it. But the RNP was really, really effective.
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