Explore our technologies and learn more about CRISPR genome engineering benefits, techniques, and more.
Learn more about clinical applications of CRISPR and how Synthego can support you from early-phase research, through process development, and into the clinic, highlighting our new sgRNA GMP manufacturing capabilities
CRISPR therapies are revolutionizing medicine, making up 70% of current gene-editing trials. To accelerate the clinical development of CRISPR cell and gene therapies, Synthego has launched its new, state-of-the-art manufacturing facility. This flyer provides an insight into our new manufacturing capacity for the production of GMP-grade CRISPR sgRNAs.
This live webinar recording explores Synthego’s cutting-edge nuclease portfolio, featuring our newest engineered nuclease, eSpOT-ON. Casey Jowdy, Senior Product Manager at Synthego, dives into its development, how its on-target and off-target profile (fidelity) compares to other Cas9 variants, and demonstrates its therapeutic potential by treating familial hypercholesterolemia. Through detailed data analysis, you will gain a deeper understanding of how eSpOT-ON enhances genome editing efficiency and how you can start using it in your work today.
Protein format Get step-by-step guidance on storing, handling, and setting up your experiments with the AccuBase Cytosine Base Editor and gRNA.
Protein format This User Guide offers key details on storing, handling, and initiating experiments with our eSpOT-ON nuclease protein and gRNA.
mRNA format This User Guide covers important guidelines for storage, preparation, and getting started with our eSpOT-ON nuclease mRNA and gRNA.
This User Guide provides essential information regarding storage, handling, quantification, and dilution of our research use sgRNAs, and preparing RNPs in a simple and easy-to-follow guide. It includes instructions for...
Done editing your cells with CRISPR and ready to prepare your samples for analysis? Synthego is here to help! This Genotyping protocol provides detailed information on everything you need to...
Over the last decade, CRISPR gene editing has revolutionized both practical research and the development of cell and gene therapies. The choice of the nuclease and gRNA format is often...
Designing guides for your CRISPR experiments is crucial. Watch this webinar to learn how to use precise gene nomenclature and select the primary transcript for designing high-quality guides for CRISPR...
CRISPR-based genome editing is emerging as a frontrunner in gene therapy research. Conventionally, viral vectors, and more recently, nanoparticles have been the choice of delivery platforms in vivo. Watch this...
Cell and gene therapies are revolutionizing next-generation therapeutics. Many researchers are now leveraging the power of CRISPR precision genome engineering in their cell and gene therapies research, from fixing mutations...
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